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Nephrology
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Low-protein rice can help reduce dietary protein intake in patients with CKD

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Consuming Low-protein rice (LPR) can help reduce dietary protein intake (DPI) in patients with chronic kidney disease (CKD), according to a study.

The amount of protein in LPR is about 4% of that in regular rice.

In this randomized, controlled trial, 51 patients with CKD stages G3aA2-G4 were randomly assigned to an LPR group or control group. All participants were counseled by dietitians to help achieve a target DPI of 0.7 g/kg ideal body weight (IBW) per day. Patients in the LPR group were instructed to consume LPR with at least 2 meals per day.

Participants were followed for 24 weeks.

The mean creatinine clearance (CCr) and estimated dietary protein intake at baseline were 52.0 ml/min and 0.99 g/kg IBW per day, respectively.  At 24 weeks, mean eDPI decreased to 0.80 g/kg IBW per day and 0.91 g/kg IBW per day in the LPR group and the control group, respectively. Urinary protein was lower in the LPR group than in the control group at 24 weeks. No significant difference between groups in CCr was found.

Reference
Hosojima M, Kabasawa H, Kaseda R, et al. Efficacy of Low-Protein Rice for Dietary Protein Restriction in CKD Patients: A Multicenter, Randomized, Controlled Study. Kidney360. 2022;3(11):1861-1870. doi: 10.34067/KID.0002982022. PMID: 36514407; PMCID: PMC9717641.

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