A post-hoc analysis of 3 clinical trials has provided promising evidence supporting the efficacy of evinacumab in reducing triglyceride-rich lipoproteins (TRLs) in patients with various lipid disorders. The analysis suggests that targeting TRL...
Amongst individuals with choroideremia (CHM), focusing on functional and anatomical parameters beyond best-corrected visual acuity (BCVA) could offer more accurate ways to track disease advancement and inform management strategies, potentially leading to improved...
Seladelpar, a peroxisome proliferator-activated receptor delta agonist, has demonstrated significant efficacy in treating primary biliary cholangitis (PBC), according to results of a Phase 3 trial. The trial showed that seladelpar resulted in a...
Polls & Quizzes
Patients with Smith-Lemli-Opitz syndrome (SLOS) with low plasma cholesterol levels treated with cholic acid supplementation experienced a significant increase in plasma cholesterol levels after 2 months, according to a pilot study. The standard...
Combined liver-kidney transplantation (CLKT) and kidney after liver transplantation (KALT) show promise in treating oxalate bone disease in pediatric patients with primary hyperoxaluria type 1 (PH1), according to a study. The study highlights...
Radiotherapy increases risk of thoracic STS in breast cancer survivors Amongst 2 cohorts of US breast cancer survivors, radiotherapy was found to be the strongest risk factor for developing thoracic soft tissue sarcoma...