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Primary Hyperoxaluria

Dental complications of primary hyperoxaluria: A rare but significant concern

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A new study highlights the challenges in managing dental complications associated with hyperoxaluria, including tooth mobility, root resorption, and radiographic alterations.

Through a review of biomedical databases, including PubMed, Medline, Google Scholar, and Embase, researchers identified 14 articles detailing the oral and dental manifestations in 15 patients with hyperoxaluria. Common findings among these cases included tooth mobility, root resorption, and radiographic alterations, often occurring at late stages of PH and frequently in conjunction with chronic renal disease.

Dental management strategies are predominantly palliative, and tooth loss is a common outcome. The lack of clinical guidelines and evidence-based recommendations further complicates the management of dental issues in hyperoxaluria patients. The study highlights the importance of early diagnosis and treatment of hyperoxaluria in preventing dental and periodontal complications.

The article underscores the need for greater awareness among dental professionals and multidisciplinary collaboration in managing these complex cases.

Reference
Hassona Y, Hassan S, Atef A, et al. Primary hyperoxaluria: Description of a new oral finding and review of literature. Spec Care Dentist. 2024;doi: 10.1111/scd.12968. Epub ahead of print. PMID: 38321570.

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