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Alagille Syndrome

New high throughput assay enhances early detection of cholestasis in newborns

A newly developed high throughput assay using ultra high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) for quantifying bile acids in dried bloodspots (DBS) enables rapid and effective early screening of cholestasis in children, according to a study. This method, which shows good performance and can be easily...

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