Ultra-widefield camera provides better visualization of the inferonasal field

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The ultra-widefield (UWF) color-fundus (CF) imaging device, Clarus 700 (Zeiss), provided better visualization of the inferonasal field compared with Daytona P200T (Optos) technology in patients with early diabetic retinopathy (DR), according to a study.

Both devices had high reliability in detecting signs of early DR.

Researchers compared total gradable areas (TGA) and differences in the projected area measured from non-mydriatic CF images of each device. The retinal periphery outside the 7 standard fields (7SF) was divided into: F3 temporal, F4 superotemporal, F5 inferotemporal, F6 superonasal, F7 inferonasal.

The stage of DR was evaluated in the 7SF and the TGA and compared between images from each device.

The analysis included 67 eyes of 67 patients.

The following were the DR stages identified in the 7SF:
-No DR (n = 36 Optos, n = 35 Clarus)
-Mild DR (n = 16 Optos, n = 17 Clarus)
-Moderate DR (n = 15)

The Optos showed significantly more area in F3 and the Clarus device showed more area in F7.

The DR stage in 4 eyes was higher on images created with Optos because of peripheral lesions that were not seen on images from the Clarus device.

The interrater reliability of DR stage between the devices “was almost perfect” in the 7SF and the TGA.

Stino H, Riessland S, Sedova A, et al. Comparison of two ultra-widefield color-fundus imaging devices for visualization of retinal periphery and microvascular lesions in patients with early diabetic retinopathy. Sci Rep. 2022;12:17449. https://doi.org/10.1038/s41598-022-21319-9