New biomarkers discovered for non-IgE mediated cow’s milk protein allergy

Researchers have identified potential new biomarkers for diagnosing non-IgE mediated cow’s milk protein allergy (NIM-CMPA) by analyzing fecal and blood samples at the point of diagnosis.

They found distinct differences in the intestinal microbiota and inflammatory markers between NIM-CMPA patients and those with IgE mediated CMPA.

These findings suggest that the identified fecal parameters could be valuable diagnostic tools for NIM-CMPA, aiding clinicians in accurately diagnosing and managing this form of allergy.

This discovery represents a significant advancement in understanding CMPA and highlights the importance of personalized approaches in allergy diagnosis and treatment.

Reference
Castro AM, Gutiérrez-Díaz I, Saiz ML, et al. Gut microbiota and inflammatory mediators differentiate IgE mediated and non-IgE mediated cases of cow’s milk protein at diagnosis. J Pediatr Gastroenterol Nutr. 2024;doi: 10.1002/jpn3.12155. Epub ahead of print. PMID: 38344848.