Study highlights continuous glucose monitoring accuracy in ICU patients

Continuous glucose monitoring (CGM) accuracy in ICU settings varies widely based on the type of CGM system and reference method used, with intravascular CGM showing better accuracy than subcutaneous CGM, according to a study.

This review analyzed 96 studies, most of which were observational (91.7%), focused on adult patients (74%), and used subcutaneous CGM (80%), with arterial blood samples serving as a reference in 40.6% of cases.

The reported accuracy, measured by mean absolute relative difference (MARD), varied widely. Subcutaneous CGM showed a MARD range of 6.6–30.5%, with newer factory-calibrated systems ranging from 9.7–20.6%. Intravascular CGM demonstrated better accuracy, with intravenous CGM showing MARD values between 5–14.2% and intraarterial CGM between 6.4–13%.

Reference
Nielsen CG, Grigonyte-Daraskeviciene M, Olsen MT, et al. Accuracy of continuous glucose monitoring systems in intensive care unit patients: a scoping review. Intensive Care Med. 2024;doi: 10.1007/s00134-024-07663-6. Epub ahead of print. PMID: 39417874.