Nephrology (45)

Novel Therapeutic Approach for Solid Organ Transplantation-associated GVHD

In this case report, 2 children with end-stage renal disease and severe primary immune deficiency (Schimke syndrome) who developed severe steroid-resistant acute graft-versus-host disease (GVHD) along with full and sustained donor T cell chimerism after isolated kidney transplantation, is presented. GVHD occurs after solid organ transplant and is often lethal....