Case Report: Sarcoma with metastatic pulmonary dissemination mimics COVID-19 clinical features
In this case report, a 13-year-old boy with fever, dry cough, persistent asthenia and impaired general condition of 2 weeks’ duration, presented to the hospital. Bloodwork showed a severe inflammatory status and X-rays were consistent with bilateral COVID-19 pneumonia. The patient developed an acute respiratory failure and COVID-19 treatment was started.
Repeated serological tests and real-time reverse transcription PCR for SARS-CoV-2 were negative and other pathogens were ruled out. An intense bilateral pulmonary dissemination with lytic vertebral bone lesions was found on a thoracic high-resolution CT scan. The patient was diagnosed with Ewing’s sarcoma with metastatic pulmonary dissemination.
The authors concluded that, “In the context of SARS-CoV-2 community pandemic, we cannot forget that COVID-19 clinical presentation is not specific and other entities can mimic its clinical features.”
Perdigón Martinelli C, Morell C, González C, et a. Metastatic pulmonary dissemination as differential diagnosis of COVID-19 disease. BMJ Case Rep. 2020;13(10):e237453. doi: 10.1136/bcr-2020-237453. PMID: 33028572.