A 24-years-old female patient known to have SLE, referred for evaluation of new-onset proteinuria.
Labs: sCrea: 0.9 mg/dL (at baseline); albumin: 2.1 g/dL; UPCR: 3.6 g/g pf creatinine; UA: 3+ protein; 0-2 RBCs.
Serology: Normal C3; Normal C4; + ANA; + anti-DS-DNA
A kidney biopsy is shown in figure 3.
The immunofluorescence is positive for IgG, IgA, IgM, C3, and C1q in a capillary wall pattern.
The biopsy is showing:
Grandin Library BuildingSix Leigh Street Clinton, New Jersey 08809