New study suggests link between chronic kidney disease, in-hospital mortality in COVID-19 patients

Chronic kidney disease (CKD) is a significant comorbidity in patients with COVID-19 and is associated with increased mortality rates, according to a new study.

The study aimed to investigate the relationship between CKD and COVID-19 mortality and included 116 patients with CKD and 147 controls confirmed with COVID-19.

The study found that the mortality rate was significantly higher in CKD patients than in non-CKD patients (30.17% vs. 4.76%, P < 0.001).

Furthermore, multivariate logistic regression analysis showed that CKD was significantly correlated with in-hospital mortality in the total sample and gender subgroups. The odds ratio for in-hospital mortality was 8.64 (confidence interval: 3.67-20.35) for the total sample, 4.77 (confidence interval: 1.38-16.40) for females, and 13.43 (confidence interval: 3.85-46.87) for males.

However, the correlation did not remain significant in the fully adjusted model in the total sample and gender subgroups. The odds ratio for in-hospital mortality was 1.70 (confidence interval: 0.35-8.19) for the total sample, 1.07 (confidence interval: 0.06-19.82) for females, and 0.87 (confidence interval: 0.07-10.33) for males.

Reference
Moeinzadeh F, Raeisi V, Babahajiani M, et al. Is Chronic Kidney Disease, a Predictor of In-Hospital Mortality in Coronavirus Disease 2019 (COVID-19) Patients? Adv Biomed Res. 2023;12:39. doi: 10.4103/abr.abr_352_21. PMID: 37057234; PMCID: PMC10086659.