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Lupus Nephritis

How does lupus nephritis affect pregnancy outcomes?

Posted on March 25, 2021

Pregnant women with active systemic lupus erythematosus (SLE) are at an increased risk of developing lupus nephritis compared to pregnant women with stable SLE, according to a study.

Researchers studied 52 women with SLE who had a total of 55 conceptions. Active SLE was present in 26 patients and stable SLE present in 29 patients. Of the 4 fetal losses that occurred in women with active SLE, 2 cases were accompanied by lupus nephritis.

“Different stages of SLE during pregnancy are closely related to maternal and fetal outcomes,” the authors concluded. “It is imperative to provide SLE women with pregnancy consultation and regular multispecialty care.”

Reference
Lu Y, Yu Y, Xia W, et al. Pregnancy outcomes in different stages of systemic lupus erythematosus among Chinese women – a retrospective cohort study. Ginekol Pol. 2021; doi: 10.5603/GP.a2020.0151. Epub ahead of print. PMID: 33751514.

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