Real life data analyzes impact of COVID-19 vaccination on clinical outcomes

This study included real life data from 582 patients hospitalized with COVID-19 (between 01/07/2021 and 11/02/2022), including 166 vaccinated patients, and 416 unvaccinated. The median age of vaccinated patients was significantly higher compared to the median age of unvaccinated patients (74 years vs 59 years). There were 5.7±2.6 months of mean latency time (±SD) from the second dose to hospitalization.

From 01/07/2021 and 01/12/2021, there was a higher risk for hospitalization for unvaccinated patients compared to vaccinated, and from 02/12/2021 and 11/02/2022, a higher risk for hospitalization amongst unvaccinated patients compared to vaccinated that had received booster dose but not for patients who only had 2 doses.

Unvaccinated patients spent more time in the hospital (7 days vs 6 days).

An age-adjusted analysis found that unvaccinated patients who were hospitalized had significantly higher mortality risk compared to vaccinated patients who were hospitalized.

Reference
Papaioannou O, Karampitsakos T, Tsiri P, et al. Clinical outcomes in vaccinated and unvaccinated patients with COVID-19: a population-based analysis. Eur Rev Med Pharmacol Sci. 2022;26(20):7705-7712. doi: 10.26355/eurrev_202210_30047. PMID: 36314348.