New proposed framework assesses preventive interventions in rare transmissible diseases

A newly proposed framework represents a pioneering advancement in the assessment of preventive interventions for rare and transmissible diseases, according to an article published in the Journal of Market Access and Health Policy.

The proposed framework, known as the ‘Rule of Prevention,’ introduces a holistic approach to assess rare, transmissible diseases, enabling a broader evaluation of prevention interventions compared to treatment options. Anchored on principles of severity, equity, and prevention benefits, this approach aims to enhance the decision-making process for preventive measures in cases of rare and transmissible diseases.

The study, guided by an objective to identify considerations for future HTAs by drawing analogies between treatment and prevention in rare diseases, found that while standard HTA methodologies can be extended to transmissible diseases, a modified approach is necessary. The inherent risk of local outbreaks and the imperative for large-scale prevention initiatives underscored the need for a specialized assessment framework capable of integrating value elements specific to prevention strategies.

Reference
Gibson E, Ollendorf DA, Simoens S, et al. Rule of Prevention: a potential framework to evaluate preventive interventions for rare diseases. J Mark Access Health Policy. 2023;11(1):2239557. doi: 10.1080/20016689.2023.2239557. PMID: 37583879; PMCID: PMC10424616.