Hematology

Donor mitochondrial DNA variants found to impact outcomes in MDS after transplantation

Mitochondrial DNA (mtDNA) variants in transplant donors, including unrelated donors, significantly impact the outcomes of allogeneic hematopoietic cell transplantation for patients with myelodysplastic syndromes (MDS), according to a study. Researchers analyzed whole-genome sequencing data from 494 donors matched to patients with MDS enrolled in the Center for International Blood and...