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IBD is bidirectionally associated with rosacea

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A bidirectional association between rosacea and inflammatory bowel disease (IBD) has been found according to a new systematic review and meta-analysis.

Rosacea and IBD are both characterized by chronic inflammation and share similarities in their pathophysiology. However, until now, the relationship between the 2 conditions has remained unclear.

The meta-analysis incorporated 8 eligible studies, examining the prevalence of rosacea in individuals with IBD compared to control groups.

The results showed that the overall prevalence of rosacea was higher in the IBD group than in the control group, with a pooled odds ratio (OR) of 1.86. Furthermore, both the Crohn’s disease and ulcerative colitis groups exhibited a higher prevalence of rosacea compared to the control group (ORs of 1.74 and 2.00, respectively).

In addition to assessing the link between IBD to rosacea, the study also investigated the reverse association. The findings indicated that individuals with rosacea had a significantly higher risk of developing IBD, Crohn’s disease, and ulcerative colitis, with incidence rate ratios of 1.37, 1.60, and 1.26, respectively, compared to those in the control group.

Jun YK, Yu DA, Han YM, et al. The Relationship Between Rosacea and Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. Dermatol Ther (Heidelb). 2023;doi: 10.1007/s13555-023-00964-6. Epub ahead of print. PMID: 37338720.