Cardiology

Researchers discover lipid signatures in familial hypercholesterolemia linked to cardiovascular risk

Specific lipid abnormalities in patients with familial hypercholesterolemia (FH) have been identified, which could serve as biomarkers for developing targeted therapies to prevent premature atherosclerotic cardiovascular disease, according to a study. Researchers investigated lipid abnormalities in the metabolic networks of 36 patients—18 with homozygous FH (HoFH) and 18 with heterozygous...