Internal Medicine

Psychiatric comorbidities in liver cirrhosis hospitalizations continue to increase

Posted on

Over the last decade, the prevalence of psychiatric comorbidities in liver cirrhosis hospitalizations has increased, with female patients having a higher association than males, according to a study.

Utilizing a national database, researchers identified patients with a primary diagnosis of liver cirrhosis.

From 2009 to 2019, the following psychiatric comorbidities increased:
-Generalized anxiety disorder (0.17% to 0.92%)
-Depression increased (7% to 12%)
-Attention deficit hyperactivity disorder (0.06% to 0.24%)
-Schizophrenia (0.59% to 0.87%)
-Schizoaffective disorder prevalence (0.10% to 0.35%)
-Post-traumatic stress disorder (0.36% to 0.93%)
-Suicidal ideation (0.23% to 0.56%)

Cirrhosis related to alcoholic liver disease and non-alcoholic fatty liver disease was associated with depression more than other causes.

Compared to males, females had a higher association with:
-Generalized anxiety disorder
-Bipolar disorder
-Chronic fatigue

Patel P, Ali H, Inayat F, et al. Racial and gender-based disparities and trends in common psychiatric conditions in liver cirrhosis hospitalizations: A ten-year United States study. World J Hepatol. 2023;15(2):289-302. doi: 10.4254/wjh.v15.i2.289. PMID: 36926245; PMCID: PMC10011900.