Patients with psoriasis and psoriatic arthritis may need closer monitoring for gout

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Psoriasis and psoriatic arthritis significantly increase the risk of hyperuricemia and gout, according to a study that emphasizes the need for clinicians to monitor and manage uric acid levels in these patients.

Researchers analyzed data from 8 studies to assess the bidirectional relationships among these conditions. Patients with psoriasis were found to have a 2.56-fold higher likelihood of developing hyperuricemia, while those with psoriatic arthritis faced a 3.56 times higher risk. Similarly, the risk of gout was nearly 5 times higher in psoriatic arthritis patients and almost twice as high in those with psoriasis.

Reference
Liu Z, Ma X, Chang T, et al. Associations between psoriasis, psoriatic arthritis and gout or hyperuricemia: a systematic review and meta-analysis. Am J Med Sci. 2025;S0002-9629(25)00921-8. doi: 10.1016/j.amjms.2025.02.006. Epub ahead of print. PMID: 39961457.