Internal Medicine

Sleep deprivation may lead to a higher risk of hypertensive heart disease

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Patients with in-hospital sleep deprivation are at a higher risk of hypertensive heart disease compared to the general population, according to a study.

In this retrospective observational study, data from the National Inpatient Sample database on 28,484,087 patients admitted from 2016 to 2019 were used to identify patients with sleep deprivation and compare inpatient cardiovascular outcomes to patients without sleep deprivation.

Overall, 2.1% (6,08,059) of admitted patients had diagnosed sleep deprivation unrelated to medical or psychiatric illness, of which 75.7% were Caucasians, 11.5% were Blacks, and 8% were Hispanics.

Although patients with sleep deprivation had a higher odds ratio of hypertensive heart disease, they had similar outcomes to the general population in terms of atrial fibrillation, heart failure with reduced ejection fraction, and heart failure with preserved ejection fraction.

Evbayekha EO, Aiwuyo HO, Dilibe A, et al. Sleep Deprivation Is Associated With Increased Risk for Hypertensive Heart Disease: A Nationwide Population-Based Cohort Study. Cureus. 2022;14(12):e33005. doi: 10.7759/cureus.33005. PMID: 36712752; PMCID: PMC9879308.